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- Bibliografia Publikacji Pracowników IUNG-PIB jest zbiorem opisów bibliograficznych publikacji pracowników Instytutu.
- Czasopisma naukowe: Polish Journal of Agronomy (kontynuacja Pamiętnika Puławskiego); Nawozy i Nawożenie ( Fertilizers and Fertilization)
- "Pamiętnik Puławski" jest kontynuacją ukazującego się w okresie międzywojennym "Pamiętnika PINGW". Publikacja zawiera syntetyczne opracowania wyników badań prowadzonych przez pracowników IUNG, opatrzone streszczeniami w języku angielskimi i rosyjskim. W latach 1961-2010 opublikowano 152 zeszyty "Pamiętnika Puławskiego". Kontynuatorem tej publikacji jest czasopismo "Polish Journal of Agronomy"
- Zbiór zawiera instrukcje upowszechnieniowe, wdrożeniowe, zalecenia agrotechniczne, materiały szkoleniowe.
- Zbiór zawiera prace doktorskie obronione w IUNG-PIB oraz Monografie i Rozprawy Naukowe
Recent Submissions
Impact of laser radiation on seeds of Berteroa incana and Setaria pumila collected from habitats exposed to artificial light at night
(Polskie Towarzystwo Inżynierii Ekologicznej, Politechnika Lubelska, 2026) Zalewski, Dariusz; Koszelnik-Leszek, Anna; Kieloch, Renata
The aim of the controlled-environment experiment was to assess the effects of semiconductor laser light on the early growth stages of Setaria pumila and Berteroa incana, whose seeds had previously been exposed to direct artificial light at night (ALAN). The seeds were collected from two maize fields differing in nighttime light pollution: 1. a site in Siechnice (Wrocław County), located near the “Siechnice” horticultural complex emitting intense nocturnal illumination, 2. a control site in Jelcz-Laskowice (Oława County), situated ca. 12 km from the emission source. The collected seeds were subjected to presowing laser irradiation at three energy levels: three-fold, fivefold, and seven-fold of the base dose of 0.25 J·cm⁻², with an exposure time of 4.1 min. Non-irradiated seeds served as the control. The study proved that the root length of seedlings of both species originating from the ALANexposed site was significantly reduced compared with the plants from the light-pollution-free area. There were also differences in germination capacity of Setaria pumila seeds – those collected from the ALAN-exposed site germinated significantly weaker than those obtained from the ALAN-free location. Laser irradiation stimulated seedling growth; however, this response was more pronounced in plants originating from the environment without nocturnal artificial lighting.
Advances in Sodium Channel Modulation in Epilepsy Therapy: Focus on Eslicarbazepine, Lacosamide and Cenobamate
(MDPI, 2026-07-28) Rudkowska, Monika; Mołdoch, Jarosław; Wronikowska-Denysiuk, Olga; Agacka-Mołdoch, Monika; Pradiuch, Anna; Wojtunik-Kulesza, Karolina
Background/Objectives: Voltage-gated sodium channels (VGSCs) are among the most important molecular targets in epilepsy therapy. Unlike classical antiseizure medications (ASMs), newer sodium channel modulators selectively affect slow inactivation or persistent sodium currents, potentially improving seizure control while preserving physiological neuronal activity. This review summarizes the pharmacology, mechanisms of action, clinical efficacy, and therapeutic potential of eslicarbazepine acetate, lacosamide, and cenobamate.
Methods: A narrative review of published clinical trials, meta-analyses, and real-world evidence was conducted. The analysis focused on sodium channel modulation, pharmacokinetic properties, efficacy in monotherapy and adjunctive therapy, and safety profiles in focal epilepsy.
Main findings of the review: Eslicarbazepine acetate and lacosamide primarily enhance slow inactivation of VGSCs, suppressing pathological repetitive neuronal firing with limited effects on normal neuronal signaling. Both agents demonstrated efficacy in monotherapy and add-on therapy, with favorable pharmacokinetic properties and a relatively low potential for drug–drug interactions. Cenobamate represents a novel therapeutic approach through preferential inhibition of persistent sodium currents combined with positive allosteric modulation of GABAA receptors. Clinical trials and real-world studies demonstrated high responder and seizure freedom rates, particularly in patients with drug-resistant focal epilepsy. The most common adverse effects across these agents included dizziness, somnolence, fatigue, and gastrointestinal symptoms, while notable safety concerns included hyponatremia with eslicarbazepine acetate and drug interactions or dose-dependent adverse effects with cenobamate. Conclusions: Recent advances in sodium channel modulation have expanded therapeutic options for focal epilepsy and support the development of more selective, mechanism-based ASM therapies. Eslicarbazepine acetate, lacosamide, and cenobamate demonstrate favorable efficacy and tolerability profiles and may improve seizure control in patients with drug-resistant epilepsy.
Response of sandy soil structure to long-term farmyard manure rates: The role of organic carbon and glomalin
(Elsevier, 2026) Juriga, Martin; Šimanský, Vladimír; Jonczak, Jerzy; Chojnacka, Aleksandra; Wójcik-Gront, Elżbieta; Pikuła, Dorota
Long‑term changes in soil structure under farmyard manure (FYM) application remain insufficiently understood in sandy soils, which are naturally poor in organic matter and highly susceptible to degradation. This study evaluates the century‑scale effects of gradually increasing annual FYM rates (0, 20, 40, 60 Mg ha⁻¹ yr⁻¹) in a 96‑year field experiment established on a Planosol in Skierniewice, central Poland. The results showed that increasing FYM inputs caused pronounced accumulation of soil organic matter. Total organic carbon (TOC) rose from 5.06% in the control to 7.53%, 11.18%, and 14.43% under 20, 40, and 60 Mg ha⁻¹, respectively (up to +185%). Total nitrogen (TN) increased from 0.45% to 1.29%, while total glomalin-related soil protein (T‑GRSP) rose by 34–77% relative to the unfertilized soil. Bulk density declined significantly only at the highest rate (from 1.69 to 1.52 g cm⁻³). Structural responses were nonlinear: mean weight diameter (MWD) increased sharply already at 20 Mg ha⁻¹(from 0.62 to 0.87 mm), and vulnerability coefficient (Kv) rose from 0.73 to 2.50, indicating higher aggregate vulnerability at 20 Mg ha⁻¹, but higher FYM rates did not further change vulnerability. Individual size-fractions of water-stable macro-aggregates (WSAma) 5–3 mm and 3–2 mm increased significantly under 20 Mg ha⁻¹, indicating an early saturation threshold. PCA confirmed that TOC, TN, and T‑GRSP are the dominant drivers of soil property changes. Overall, the greatest soil structural change occurred between the control and 20 Mg ha⁻¹ FYM. This study evaluated soil-level endpoint responses; crop productivity, crop-rotation performance, and environmental impacts were not measured and therefore cannot be inferred from the present dataset.
Genetic diversity and differentiation of two narrowly endemic Origanum species in Morocco: implications for conservation
(Springer, 2026) Aboukhalid, Kaoutar; Machon, Nathalie; Lambourdière, Josie; Bakha, Mohamed; Neffa, Mounsef; Korbecka-Glinka, Grażyna; Khiraoui, Abdelkarim; Choudhary, Ravish; Lamiri, Abdeslam; Al Faiz, Chaouki
Oregano is a highly valued aromatic and medicinal herb in the Mediterranean, appreciated for its ecological, medical, and culinary properties. This paper aims to explore genetic variation and population structure within O. elongatum and O. grosii populations across their natural range in Morocco by analyzing 13 microsatellites (SSRs). Despite the restricted habitat of O. elongatum, the level of genetic diversity in this species is rather high (Ho = 0.455; He = 0.429); however, O. grosii possesses a reduced level of genetic diversity (Ho = 0.285; He = 0.291) while demonstrating more genetic differentiation between populations. Principal Coordinates Analysis and STRUCTURE analysis revealed four clusters that largely reflected the geographic origin of these plants and clearly separated the two taxa. These results indicate strong genetic differentiation and distinct population structures, supporting their differentiation as separate genetic entities. However, further integrative studies combining genomic and morphological data are needed to confirm their taxonomic status. No significant relationship between genetic and geographic distances was detected, indicating the absence of isolation by distance in the species studied. These findings underscore the necessity of developing species-specific or unit-based approaches to their conservation. Overall, this study illustrates how genetic data can inform conservation planning for rare endemic plants in ecologically sensitive regions, providing a model applicable to other Mediterranean mountain ecosystems facing climate and land-use pressures.
Development of Gluten-Free Corn Snacks Enriched with White Mulberry Fruit: Polyphenolic Composition, Antioxidant Activity and In Vitro Gastrointestinal Stability of Phenolic Compounds
(MDPI, 2026) Kasprzak-Drozd, Kamila; Ziółkiewicz, Agnieszka; Wojtunik-Kulesza, Karolina; Gancarz, Marek; Kowalska, Iwona; Misiurek, Justyna; Wójciak, Magdalena; Sowa, Ireneusz; Oniszczuk, Tomasz; Combrzyński, Maciej; Oniszczuk, Anna
The aim of this study was to evaluate the effect of adding white mulberry (Morus alba L.) fruit to extruded corn snacks on their polyphenol profile, antioxidant properties, acetylcholinesterase (AChE) inhibitory activity and the preservation of phenolic compounds in an in vitro digestion model. Mixtures of corn grits with 0, 10, 15 and 20% dried mulberry fruit were extruded at temperatures of 100, 120 and 140 ◦C, and then the total polyphenol content (TPC) and antioxidant activity (IC50 for DPPH) were determined. For selected samples (0%, 140—3E; 15% mulberry, 140—9E; mulberry—13E), further antioxidant tests (FRAP, CUPRAC, Fe2+ chelation) were performed, the phenolic compound profile (UHPLC) and AChE inhibition were assessed, and a two-step in vitro digestion was conducted. The addition of mulberry significantly increased TPC- and free-radical-scavenging capacity compared to the control sample, with snacks containing 15% mulberry extruded at 140 ◦C showing approximately a 3.5-fold higher TPC than the control, while dried mulberry fruit itself exhibited about a five-fold higher TPC than this enriched snack. Among the snacks, the most favorable DPPH-radical-scavenging effect was obtained for the variant with 20% mulberry at 120 ◦C (IC50 = 0.176 mg/mL), whereas the mulberry fruit extract reached an IC50 of 0.0926 mg/mL. In a two-step in vitro digestion model, the mulberry-enriched snack with 15% fruit retained 69.3% of its initial TPC after the gastric phase and 33.3% after the intestinal phase, compared with 55.0% and 20.0%, respectively, for the control snack, confirming a partial but meaningful preservation of phenolic compounds under simulated gastrointestinal conditions. UHPLC analysis confirmed that mulberry and the enriched snacks are a rich source of chlorogenic acids and their isomers, as well as quercetin and kaempferol glycosides, which largely survived the two-step in vitro digestion, despite an observed decrease in TPC after the gastric stage and a further reduction after the intestinal stage. At the same time, mulberry extract and mulberry-enriched snacks exhibited high antioxidant activity in all tests conducted and in vitro AChE inhibitory activity, suggesting that Morus alba L. fruit has the potential to be used as a natural functional ingredient in the production of gluten-free snacks with antioxidant and potentially neuroprotective properties.