Browsing by Author "Skomra, Urszula"
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Item Analiza uwarunkowania ekonomiczno-rynkowych produkcji chmielu w Polsce(Instytut Uprawy Nawożenia i Gleboznawstwa Państwowy Instytut Badawczy, 2015) Skomra, UrszulaItem Anticholinesterase Activity and Bioactive Compound Profiling of Six Hop (Humulus lupulus L.) Varieties(MDPI, 2024) Sagan, Bartłomiej; Czerny, Bogusław; Stasiłowicz-Krzemień, Anna; Szulc, Piotr; Skomra, Urszula; Karpiński, Tomasz M.; Lisiecka, Jolanta; Kamiński, Adam; Kryszak, Aleksandra; Zimak-Krótkopad, Oskar; Cielecka-Piontek, JudytaHops (Humulus lupulus L.) are widely recognized for their use in brewing, but they also possess significant pharmacological properties due to their rich bioactive compounds, with many varieties exhibiting diverse characteristics. This study investigates the chemical composition and biological activities of extracts from six hop varieties, focusing on quantifying xanthohumol and lupulone using High-Performance Liquid Chromatography (HPLC) and Total Phenolic Content (TPC) analysis. The hop varieties demonstrated significant variability in bioactive compound concentrations, with Aurora showing the highest xanthohumol (0.665 mg/g) and Zwiegniowski the highest lupulone (9.228 mg/g). TPC analysis revealed Aurora also had the highest phenolic content (22.47 mg GAE/g). Antioxidant activities were evaluated using DPPH, ABTS, CUPRAC, and FRAP assays, with Aurora and Oregon Fuggle displaying the most potent capacities. Aurora, in partic ular, showed the highest activity across multiple assays, including significant acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and tyrosinase inhibition, with IC50 values of 24.39 mg/mL, 20.38 mg/mL, and 9.37 mg/mL, respectively. The chelating activity was also assessed, with Apolon demonstrating the strongest metal ion binding capacity (IC50 = 1.04 mg/mL). Additionally, Aurora exhibited the most effective hyaluronidase inhibition (IC50 = 10.27 g/mL), highlighting its potential for anti-inflammatory applications. The results underscore the influence of genetic and environmental factors on the bioactive compound profiles of hop varieties and their biological activity offering promising avenues for pharmaceutical and nutraceutical applications. However, further studies are needed to fully understand the potential interactions between hop cones components.Item Breeding of triploid common hop cultivars (Humulus lupulus L.)(Instytut Uprawy Nawożenia i Gleboznawstwa – Państwowy Instytut Badawczy w Puławach) Trojak-Goluch, Anna; Skomra, UrszulaItem Chmiel jako źródło bioaktywnych metabolitów wtórnych dla przemysłu piwowarskiego i farmaceutycznego(Instytut Uprawy Nawożenia i Gleboznawstwa Państwowy Instytut Badawczy, 2012) Agacka, Monika; Skomra, UrszulaItem Główne kierunki hodowli chmielu w Polsce i na świecie(Instytut Uprawy Nawożenia i Gleboznawstwa Państwowy Instytut Badawczy, 2008) Skomra, UrszulaItem Hops as a source of biologically active compounds(Instytut Uprawy Nawożenia i Gleboznawstwa – Państwowy Instytut Badawczy w Puławach, 2020) Przybyś, Marcin; Skomra, UrszulaItem Kierunki badań naukowych wspierające doskonalenie genotypów chmielu(Instytut Uprawy Nawożenia i Gleboznawstwa Państwowy Instytut Badawczy, 2012) Skomra, Urszula; Przybyś, Marcin; Trojak-Goluch, AnnaItem Mączniak prawdziwy – groźna choroba chmielu(Instytut Uprawy Nawożenia i Gleboznawstwa Państwowy Instytut Badawczy, 2008) Skomra, UrszulaItem Metodyka integrowanej produkcji chmielu(Instytut Uprawy Nawożenia i Gleboznawstwa Państwowy Instytut Badawczy) Skomra, UrszulaItem Postęp w technologii produkcji chmielu ? najważniejsze rozwiązania techniczne oraz osiągnięcia hodowli(Instytut Uprawy Nawożenia i Gleboznawstwa Państwowy Instytut Badawczy, 2018) Skomra, UrszulaItem Stability of the hop bitter acids during long-term storage of cones with different maturity degree(Instytut Uprawy Nawożenia i Gleboznawstwa – Państwowy Instytut Badawczy w Puławach) Skomra, Urszula; Koziara-Ciupa, MartaItem Stan aktualny i perspektywy uprawy chmielu w Polsce(Instytut Uprawy Nawożenia i Gleboznawstwa Państwowy Instytut Badawczy, 2012) Skomra, UrszulaItem The Expression of Genes Involved in Synthesis of Bitter Acids and Xanthohumol and the Content of These Compounds in Aroma and Bitter Hop under Reduced Nitrogen Fertilisation(MDPI, 2024) Czubacka, Anna; Skomra, Urszula; Agacka-Mołdoch, Monika; Koziara-Ciupa, MartaHop (Humulus lupulus) is cultivated for industrial purposes, primarily for brewing, but also for pharmaceutical and cosmetic applications. The hop cones are valued for their secondary metabolites, including bitter acids and prenylflavonoids. The objective of the presented study was to investigate the impact of reducing nitrogen fertilisation on the activity of genes involved in the production of bitter acids and xanthohumol in cultivars Lubelski (aroma) and Magnat (bitter) grown in the field. Furthermore, the content of these compounds was determined. The results demonstrated that the majority of studied genes were expressed at a similar level despite the reduction in the nitrogen dose by 25–30%. Nitrogen dose influenced the activity of genes BCAT2, HS1, and PAL. Moreover, the differences in gene expression were observed between cultivars and developmental stages. The reduction in nitrogen dose did not result in a reduction in secondary metabolite content. The content of alpha and beta acids in Magnat was approximately 14.8% and 3.2%, respectively, while in Lubelski it was approximately 7.7% and 5.8%, respectively. The content of xanthohumol in both cultivars was approximately 0.7%.Item Use of canonical variate analysis for the multivariate assessment of hop cultivars (Humulus lupulus L.)(Instytut Uprawy Nawożenia i Gleboznawstwa – Państwowy Instytut Badawczy w Puławach, 2008) Bocianowski, Jan; Skomra, UrszulaItem Uzyskiwanie zdrowych sadzonek chmielu jako element restrukturyzacji odmianowej(Instytut Uprawy Nawożenia i Gleboznawstwa Państwowy Instytut Badawczy, 2008) Doroszewska, Teresa; Skomra, Urszula; Przybyś, Marcin; Czubacka, Anna; Grudzińska-Sterno, Magdalena