Browsing by Author "Acharya, Krishnendu"

Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    Chemical Composition, Biological Activity, and Health-Promoting Effects of Withania somnifera for Pharma-Food Industry Applications
    (Wiley, 2021) Sharifi-Rad, Javad; Quispe, Cristina; Ayatollahi, Seyed Abdulmajid; Kobarfard, Farzad; Staniak, Mariola; Stępień, Anna; Czopek, Katarzyna; Sen, Surjit; Acharya, Krishnendu; Matthews, Karl R.; Sener, Bilge; Devkota, Hari Prasad; Kırkın, Celale; Ozçelik, Beraat; Victoriano, Montserrat; Martorell, Miquel; Suleria, Hafiz Ansar Rasul; Alshehri, Mohammed M.; Chandran, Deepak; Kumar, Manoj; Cruz-Martins, Natalia; Cho, William C.
    The Withania genus comes from the Solanaceae family and includes around 23 species, spread over some areas of the Mediterranean, Asia, and East Africa. Widely used in traditional medicine for thousands of years, these plants are rich in secondary metabolites, with special emphasis on steroidal lactones, named withanolides which are used as ingredients in numerous formulations for a plethora of diseases, such as asthma, diabetes, arthritis, impotence, amnesia, hypertension, anxiety, stress, cancer, neurodegenerative, and cardiovascular diseases, and many others. Among them, Withania somnifera (L.) Dunal is the most widely addressed species from a pharmacological and agroindustrial point of view. In this sense, this review provides an overview of the folk uses, phytochemical composition, and biological activity, such as antioxidant, antimicrobial, anti-inflammatory, and cytotoxic activity of W. somnifera, although more recently other species have also been increasingly investigated. In addition, their health-promoting effects, i.e., antistress, anxiolytic, adaptogenic, antirheumatoid arthritis, chemoprotective, and cardiorespiratory-enhancing abilities, along with safety and adverse effects are also discussed.
  • No Thumbnail Available
    Item
    Santalum Genus: phytochemical constituents, biological activities and health promoting-effects
    (De Gruyter, 2022) Sharifi-Rad, Javad; Quispe, Cristina; Turgumbayeva, Aknur; Mertdinç, Zehra; Tütüncü, Sena; Aydar, Elif Feyza; Özçelik, Beraat; Stępień-Warda, Anna; Staniak, Mariola; Koziróg, Anna; Otlewska, Anna; Antolak, Hubert; Sen, Surjit; Acharya, Krishnendu; Lapava, Natallia; Emamzadeh-Yazdi, Simin; Martorell, Miquel; Kumar, Manoj; Varoni, Elena Maria; Iriti, Marcello; Calina, Daniela
    Santalum genus belongs to the family of Santalaceae, widespread in India, Australia, Hawaii, Sri Lanka, and Indonesia, and valued as traditional medicine, rituals and modern bioactivities. Sandalwood is reported to possess a plethora of bioactive compounds such as essential oil and its components (α-santalol and β-santalol), phenolic compounds and fatty acids. These bioactives play important role in contributing towards biological activities and health-promoting effects in humans. Pre-clinical and clinical studies have shown the role of sandalwood extract as antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, neuroleptic, antihyperglycemic, antihyperlipidemic, and anticancer activities. Safety studies on sandalwood essential oil (EO) and its extracts have proven them as a safe ingredient to be utilized in health promotion. Phytoconstituents, bioactivities and traditional uses established sandalwood as one of the innovative materials for application in the pharma, food, and biomedical industry.